Moxifloxacin Modulated TGF-b1-Related Interleukin-12 Secretion in Corneal Fibroblasts

نویسندگان

  • Tsan-Chi Chen
  • Shu-Wen Chang
چکیده

Citation: Chen T-C, Chang S-W. Moxifloxacin modulated TGF-b1-related interleukin-12 secretion in corneal fibroblasts. Invest Ophthalmol Vis Sci. 2017;58:5692–5702. DOI:10.1167/ iovs.17-21944 PURPOSE. To explore the variability in interleukin-12 (IL-12) secretion in human corneal fibroblasts (HCFs), the effects of IL-12 on HCF viability and migration, and the effects of recombinant human transforming growth factor-b1 (rhTGF-b1) and moxifloxacin (MOX) on IL-12 expression.

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Moxifloxacin Modulated TGF-β1-Related Interleukin-12 Secretion in Corneal Fibroblasts.

Purpose To explore the variability in interleukin-12 (IL-12) secretion in human corneal fibroblasts (HCFs), the effects of IL-12 on HCF viability and migration, and the effects of recombinant human transforming growth factor-β1 (rhTGF-β1) and moxifloxacin (MOX) on IL-12 expression. Methods IL-12 secretion in 27 primary HCFs incubated with rhTGF-β1 and/or MOX was analyzed using immunoblotting....

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تاریخ انتشار 2017